Pancuronium bromide

TEXAS – Texas prison system has drugs for 23 executions

May 19, 2012  source : AP

After prodding from Texas AG, prison system says it has enough drugs to execute 23 inmates
Texas prison officials disclosed Friday they have enough lethal drugs to execute as many as 23 people.
In response to this week’s opinion from the state attorney general’s office that said the Texas Department of Criminal Justice could not withhold information about the drug supply, the department said it currently has 46 2.5-gram vials of pentobarbital. A 5-gram dose — about 3.4 ounces — is the 1st lethal drug used during each execution in Huntsville, according to Texas execution procedures.
The prison agency said it had similar supplies of 2 other drugs also administered to condemned inmates. It did not, though, identify suppliers of the lethal drugs, which the opinion also had addressed.
Executions also involve 100 milligrams of pancuronium bromide and 140 milliequivalents of potassium chloride. Texas has 290 10-milligram vials of the pancuronium bromide — 10 are required per execution — and 737 20-milliequivalent vials of potassium chloride — 7 per punishment.
The department’s written procedures call for a matching set of drugs and syringes “in case unforeseen events make their use necessary.” But in a brief statement emailed to reporters late Friday, the agency said a backup set of lethal drugs for executions “is not actually prepared, but an additional dose is available if needed.”
The attorney general’s opinion, dated Monday, was an answer to public information requests filed earlier this year by the Austin American-Statesman and British newspaper The Guardian.
Prison officials had argued that releasing the information could be harmful to employees and provide death penalty opponents a way to harass the drug suppliers with the hope firms would refuse to do business with the state.
“We find your arguments as to how disclosure of the requested drug quantities would result in the disruption of the execution process or otherwise interfere with law enforcement to be too speculative,” Sean Opperman, an assistant attorney general, wrote in the opinion.
The prison agency had 30 days to comply with the opinion or to challenge it in court. The status of the supplier question was not immediately clear.
Opperman said that, while the attorney general’s office “acknowledge(s) the department’s concerns,” the corrections department didn’t show how disclosure of the information “would create a substantial threat of physical harm to any individual.”
Department officials previously had indicated they had a sufficient supply to handle upcoming executions. At least five are scheduled for this summer, including one early next month.
Last year, one of the drugs Texas had used in the process, sodium thiopental, became unavailable when its European supplier bowed to pressure from death penalty opponents and stopped making it. No other vendor could be found, so the drug was replaced by pentobarbital.
The physical effects of pentobarbital on condemned inmates have not been noticeable during the executions, but the financial cost to the state has risen considerably. Prison officials put the cost of the previous mixture at $83.35. It’s now $1286.86, with the higher cost primarily due to pentobarbital.

US – US hospitals face medicine shortages as crucial supplies diverted to executions

May 8, 2012 Source : http://www.reprieve.org.uk

US hospitals are facing shortages of a key medicine used in surgical anaesthesia as death rows stockpile the same drug for use in executions, new figures have shown.

Prisons across the USA are holding large stockpiles of pancuronium bromide, a paralysing agent designed to relax muscles during surgery, in order to use it as part of a three-drug execution ‘cocktail.’

The US Food and Drug administration (FDA) has repeatedly warned that the country is facing shortages of the medicine, which date back as far as 2010. Yet various Departments of Corrections, which don’t use the drug for medicinal purposes, but only in executions, are hoarding large quantities. Virginia alone, for example, holds 60 vials of the drug, enough to treat roughly 50-60 patients in emergency medical operations.

The executing states’ behaviour is particularly controversial as the use of pancuronium – which slowly suffocates the prisoner – is not even necessary in executions, as a third drug is employed to stop the heart. The second stage is purely cosmetic, paralysing the prisoner so that onlookers can’t see any signs that they might be in distress. Worse still, by paralysing the prisoner, the use of pancuronium creates a serious risk that they will be left unable to signal that the first drug, an anaesthetic, has failed to work – and therefore will die in excruciating pain, unable to move or even to speak.

Legal action charity Reprieve is calling on manufacturers to put in place procedures to ensure that the drug reaches only legitimate, medical users, and is not diverted to execution chambers – which will also help to reduce the shortages hospitals currently face.

Pancuronium bromide is manufactured by Hospira, a company which has repeatedly stated its opposition to the use of its medicines in executions. Thus far, however, it has taken no active steps to prevent this use. The result is that Hospira’s pancuronium bromide is currently unavailable for the doctors who have legitimate medical need for it, while executioners apparently have ample supplies.  

Reprieve investigator, Maya Foa said: “Regardless of your views on the death penalty, it cannot be right that hospitals are facing shortages of medicines while executing chambers sit on huge stockpiles. These drugs are being diverted from their legitimate, medical use in order to kill. Manufacturers like Hospira must put in place controls to ensure this is not allowed to happen.”